3D imaging of skin reveals a hair follicle, its gland, and nerve network with stunning clarity, advancing research in alopecia and inflammatory skin disease.
3D imaging of the human placenta reveals vascular networks and cellular detail with a-SMA (green) and TO-PRO-3 (magenta). A striking view that advances maternal–fetal research.
Computational H&E staining, combined with 3D imaging, reveals the full structure of tertiary lymphoid structures (TLS) in NSCLC, overcoming 2D sampling bias and enabling the accurate quantification of volume, maturity, and spatial context.
Computational H&E staining combined with non-destructive 3D imaging reveals the true complexity of tertiary lymphoid structures (TLS) in NSCLC. Unlike thin 2D sections that risk misclassification, Alpenglow’s 3Di platform captures entire TLS morphology, volume, and cellular composition, delivering accurate insights into immune architecture and tumor context.
3D segmentation of prostate glands using synthetic CK8 immunofluorescence derived from fluorescent H&E analogues. By combining image-translation models with traditional computer-vision methods, researchers achieved whole-biopsy 3D gland segmentation without manual labeling.
3D fluorescence imaging of human lung tissue stained with Fast Green reveals collagen architecture for fibrosis and tissue remodeling research.
3D imaging of human skin biopsy stained with tryptase, TO-PRO-3, and PGP9.5 reveals mast cell–nerve interactions for dermatology and oncology research.
3D imaging of prostate organoids stained with TO-PRO-3 and eosin reveals spatial heterogeneity, cellular interactions, and microenvironmental detail.
3D fluorescence imaging of prostate tissue stained with Fast Green reveals the collagen architecture, orientation, and density, providing insights beyond 2D histology.
High-resolution 3D imaging of human tonsil tissue stained with YO-PRO-1 for nuclei and tryptase for mast cells.
3D imaging of prostate organoids with LUMI shows ROI selection, multi-well scanning, and high-resolution analysis using TO-PRO-3 and eosin staining.
FFPE colorectal tissue stained with YO-PRO-1 and anti-CD8 imaged in 3D at 2 μm/pixel on Aurora HOTLS. Quantification of CD8+ lymphocytes across whole section.
3D imaging of human placenta tissue stained with SMA, HLA-G, and CD31. From whole-tissue scans to single-cell resolution, uncover tissue complexity in detail.
Scout 3D imaging of a human DRG sample from AnaBios with computational H&E staining, ToPro-3 for nuclei, and eosin for protein structures.
Zoomed 3D imaging of human DRG sample from AnaBios with computational H&E staining, ToPro-3 for nuclei, and eosin for protein structures.
3D imaging of cleared liver tissue stained with Collagen III, followed by segmentation analysis using a pixel classifier to highlight fibrosis.
3D spatial biology image of liver biopsy segmented with AI, highlighting fibrosis (cyan) and steatosis (yellow) for quantitative pathology insights.
A 3D fly-through of liver tissue stained with computational hematoxylin and eosin, showcasing structures beyond traditional 2D pathology.
3D imaging of human colon stained with Calretinin reveals dense innervation of the mucosa and submucosa.
A 3D scan of a human ileocecal sample with over 840 billion pixels and 2,350 mm³ volume, imaged on Alpenglow’s Aurora HOTLS platform.
Large cleared human brain slice (10 × 7 × 0.3 cm) imaged at 0.17 microns per pixel using the CUBIC protocol for high-resolution volumetric analysis.