3Dm: Advanced Data Management for Large-Scale 3D Tissue Imaging

Unlock the power of automated registration, alignment, and flat field correction for your large 3D imaging datasets.

What 3Dm™ Does

3Dm™ pipeline processes large and ultra-large 3D imaging datasets using an automated workflow that reduces manual intervention and increases consistency.
It aligns images, stitches volumes, corrects illumination, and integrates multi-channel fluorescence data within one structured pipeline.

Automated 3D Stitching & Registration

Precise Alignment

Automatically stitch images post-imaging, delivering high accuracy and efficiency across large datasets.

Precise Alignment of Light Sheet Images

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Reduced Manual Intervention

The automated workflow minimizes manual steps, saving time while maintaining consistent processing.

Enhanced Data Integrity

Standardized processes reduce variability and help preserve dataset quality across experiments.

Uniform Illumination

Corrects for uneven illumination across the imaging field, providing consistent brightness and contrast.

Flat‑Field Correction for 3D Tissue Imaging

Comparative images labeled 'Before' and 'After' showing a surface under blue lighting.

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Artifact Removal

Artifacts and distortions are detected and corrected to produce cleaner, more accurate datasets.

Improved Analysis

Enhanced image uniformity supports clearer feature identification and downstream quantification.

Destriping

Stripe artifacts from uneven illumination or shadows are automatically recognized and smoothed to create cleaner 3D volumes.

Deconvolved, Multi-Channel Fluorescence Integration

Integrated Channels

Deconvolved and integrated multiple fluorescence channels effortlessly, creating a comprehensive dataset for seamless analysis.

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Accurate Co-Localization

Co-localization of markers is maintained during processing, supporting the interpretation of cellular and tissue-level interactions.

Streamlined Workflow

Combining channels and preparing them for analysis is handled automatically to increase speed and consistency.

Ultra-Large Dataset Processing Capabilities

Scalable Processing

The system handles datasets ranging from gigabytes to terabytes using a fully automated pipeline designed for large-volume imaging.

High-Throughput

GPU-accelerated processing supports high-throughput workflows and rapid handling of multiple samples.

Resource Optimization

Advanced algorithms balance workload, manage memory and maintain stable performance for demanding datasets.

Applications & Success Stories

  • Accelerate drug development with enhanced image analysis and data management.

  • Enhance clinical research with seamless integration of multi-channel fluorescence data.

  • Discover novel biomarkers with ultra-large dataset processing capabilities.

Discover the 3Dm™ within the Aurora™ Platform
View the Webinar on 3D Tissue Imaging and Image Artifacts
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