Use cases
3D tissue imaging use cases across spatial biology
Explore how 3D tissue imaging, digital pathology, AI-powered analysis, spatial profiling, and quantitative tissue analysis can support research programs across intact tissue samples and volumetric datasets.
Use case library
Explore 3D imaging across intact tissue applications
Review application examples covering dermatology, immuno-oncology, tertiary lymphoid structures, 2D versus 3D tissue analysis, and ground-truth data for spatial biology research.
3D imaging of atopic dermatitis
See how full-volume 3D imaging of skin biopsies reveals immune–epithelial interactions, nerve fibers, and microvascular changes. The use case demonstrates how intact-tissue analysis can quantify inflammatory patterns and spatial changes associated with treatment.
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Decoding immune exclusion in 3D
Explore how 3D tissue imaging and AI-powered analysis map lymphocyte distribution, exclusion zones, and tumor microenvironment architecture across intact tumor samples. The study supports investigation of spatial patterns associated with differential treatment response.
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2D versus 3D tissue analysis
Compare conventional 2D histology with 3D imaging of the same specimen. The use case shows how isolated sections can undercount structures, miss rare features, or incompletely represent tissue architecture, while whole-tissue datasets provide a more complete spatial reference.
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3D segmentation of tertiary lymphoid structures
See how tertiary lymphoid structures in non-small cell lung cancer can be segmented and quantified in 3D, including their size, location, volume, and spatial organization. The workflow supports TLS biomarker research in immuno-oncology.
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Ground-truth 3D data in immuno-oncology
Explore how whole-tissue 3D imaging, Aurora workflows, and quantitative analysis can support immuno-oncology research through full-volume tissue context and image-linked spatial measurements.
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