Turn Tissue into Data with 3D Tissue Imaging and Spatial AI

Intact 3D tissue imaging, spatial profiling, and quantitative AI analysis in a single, end-to-end imaging platform.

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Aurora™: 3D Spatial Biology Platform

End-to-end 3D imaging, data management, and AI analysis in one platform.

3Di

Advanced Tissue Imaging

Dual-path light-sheet for whole samples and high-resolution detail, operated with LUMI interface.

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3Dm

Automated Data Management

Alignment, organization, and viewing of large 3D datasets, ready for analysis.

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3Dai

AI-Driven Image Analysis

Quantify cells, structures, and spatial patterns for decision-grade metrics.

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LEARN ABOUT 3D IMAGING SERVICES

Solutions for your Role

  • Reveal the full structure of skin in 3D. Alpenglow empowers dermatology researchers to analyze tumor margins, vessels, and inflammation with clarity.

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  • Alpenglow helps immunologists decode the tissue microenvironment in 3D, revealing immune infiltration, spatial relationships, and treatment response.

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  • From biodistribution to mechanism of action, Alpenglow’s 3D imaging platform gives translational scientists the clarity needed to drive better therapeutic decisions.

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  • Simplify whole-tissue imaging and accelerate user workflows. The 3Di HOTLS microscope combines speed, clarity, and accessibility, ideal for any imaging facility.

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  • Alpenglow helps group leaders deliver faster, deeper insights with 3D imaging, replacing slicing with full-volume clarity and reproducible data.

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  • Alpenglow helps pathologists move beyond flat slides, offering 3D views of intact tissue to reveal margins, patterns, and structures missed in 2D.

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See What You’ve Been Missing: Ground-Truth 3D Data

Alpenglow captures whole tissues intact in 3D, revealing architecture and cellular context with decision-grade clarity that conventional slides cannot provide.

Aurora™ platform, from tissue to usable data

  • Image intact tissue

  • Process and manage large volumes

  • Quantify with AI for reproducible segmentations and metrics

Why ground-truth 3D matters

Whole-tissue imaging preserves architecture and scale
• Preserve true 3D tissue structure across volumes
• Measure cell populations and distances
• Align imaging with outcomes for model training

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Reveal Hidden Biology with 3D Tissue Imaging

Whole-tissue 3D imaging and AI-powered analysis uncover spatial insights across research and clinical domains.


Dermatology

The 3D Derm Score Assay visualizes intact skin architecture, mapping nerves, immune cells, and inflammation across the full tissue depth.

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Immuno-Oncology

​The 3D I/O Pro Assay characterizes tumor-immune interactions in 3D, revealing immune infiltration and stromal organization within the microenvironment.

See the 3D I/O PRO ASSAY

Multi-Field Capabilities

A flexible 3D platform for neuroscience, immunology, and translational studies — enabling volumetric mapping of complex tissue biology.

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Alpenglow Biosciences in the News

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ABOUT ALPENGLOW

Alpenglow Biosciences accelerates drug development and improves clinical diagnostics through AI-enabled 3D imaging technology. Our platform delivers new biological insights and more accurate data by digitizing entire samples while preserving tissue for molecular analysis. Partners benefit from exclusive technology and a greater understanding of their biology. Five of the top 10 pharmaceutical companies collaborate with Alpenglow to uncover new insights, streamline timelines, and improve success rates.

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