This dataset presents a high-resolution 3D view of human skin, highlighting the architecture of a hair follicle and its associated gland, along with the surrounding nerve network. The imagery was captured using Alpenglow Biosciences’ Aurora™ 3Di Hybrid Open Top Light Sheet microscope, a non-destructive system that preserves tissue integrity and reveals structures invisible in 2D histology.

Once imaged, the data is processed through 3Dm data management and analyzed with 3Dai AI-powered spatial analysis, transforming visual information into quantitative insights. This workflow enables precise measurements of follicle structure, glandular organization, and neural complexity, advancing research into alopecia, inflammatory skin conditions, and dermatological biology.

This dataset demonstrates how 3D histology goes beyond imaging, delivering decision-grade data that can inform both fundamental science and translational applications.