This dataset showcases a whole skin punch biopsy stained for CD45, imaged with cutting-edge 3D technology.

The visualization highlights the spatial distribution of lymphocytes within the epidermis and dermis, revealing how immune cells cluster around nerve networks and integrate into the skin’s complex architecture.

Advanced data managementand AI-powered segmentation enable precise mapping of lymphocyte distribution, capturing patterns invisible to conventional 2D histology.

These results not only provide stunning imagery but also uncover fundamental insights into immune–neural interactions in skin, fueling progress in dermatology research and reshaping our understanding of inflammatory skin disease.

By combining whole-tissue 3D imaging with quantitative analysis, this work demonstrates the transformative potential of digital pathology and spatial biology.

See our AD use case.