This dataset shows a mouse skin biopsy imaged in 3D using fluorescence labeling. Nerves are labeled with PGP9.5, nuclei with Yo-pro-1, and Nav1.8 highlights sensory neuron populations. The full tissue volume reveals dense and tortuous nerve branching across the dermal and epidermal layers.

Unlike 2D histology, this approach preserves spatial continuity, enabling direct quantification of branching patterns, nerve density, and relationships to surrounding structures. Imaging intact tissue allows accurate analysis of complex neural architectures that are otherwise fragmented in sectioned samples.