Learning Wednesday
Practical insights on 3D tissue imaging and spatial biology.
A weekly LinkedIn series from Alpenglow Biosciences, collected here for easy access to research papers, concepts, and practical examples in 3D tissue imaging, digital pathology, spatial profiling, volumetric datasets, and AI-powered analysis.
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Explore the 3D imaging literature by research area
Move directly into the topics most relevant to your work, from intact-tissue imaging and spatial omics to digital pathology, inflammation, cancer biology, and light-sheet microscopy.
Nuclear morphology and 3D imaging for cellular neighborhoods
A Learning Wednesday paper note on 3D nuclear morphology and cellular neighborhood profiling.
Why three-dimensional tissue assessment matters
A Learning Wednesday paper note on why 3D assessment changes tissue composition measurements.
Hybrid open-top light sheet microscopy for cleared tissues
A Learning Wednesday paper note on hybrid open-top light sheet microscopy for multiscale cleared tissue imaging.
VORTEX: AI-driven 3D spatial transcriptomics
A Learning Wednesday paper note on AI-enabled 3D spatial transcriptomics.
Cleared human melanoma analyzed in 3D
A Learning Wednesday paper note on 3D analysis of cleared human melanoma tissue.
3D imaging of cleared human skin biopsies with light sheet microscopy
A Learning Wednesday paper note on light sheet microscopy for full-depth skin biopsy visualization.
Skin-iDISCO+ for 3D analysis of human cutaneous vasculature
A Learning Wednesday paper note on tissue clearing and 3D analysis of human cutaneous vasculature.
3D imaging of upper tract urothelial carcinoma
A Learning Wednesday paper note on 3D pathology approaches for upper tract urothelial carcinoma diagnosis.
Harnessing non-destructive 3D pathology
A Learning Wednesday paper note on digital pathology.
Prostate cancer risk stratification with non-destructive 3D pathology
A Learning Wednesday paper note on non-destructive 3D pathology and AI-assisted prostate cancer risk stratification.
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Continue exploring the 3D imaging literature
Explore additional publications and research summaries covering intact-tissue imaging, digital pathology, spatial profiling, light-sheet microscopy, and AI-powered quantitative analysis.