Derm Score Assay enables quantitative 3D tissue analysis in HS and burning mouth syndrome at SID 2026
At SID 2026, Alpenglow Biosciences’ dermatology pipeline will be featured across multiple studies applying 3D tissue imaging to inflammatory and neuropathic skin conditions.
These works utilize the Derm Score Assay, including Hybrid Open Top Light Sheet (HOTLS) microscopy, to analyze tissue architecture and cellular organization across full biopsy volumes.
Two poster presentations highlight this approach:
• LB1098
A pilot study utilizing 3D imaging to characterize burning mouth syndrome - with the University of Utah
Poster Session
Friday, May 15, 2026, 4:30 pm – 6:00 pm
• 0088
Spatial characterization of mast cells and nerve fibers in hidradenitis suppurativa using hybrid open-top light-sheet microscopy - with the University of Minnesota
Poster Session
Friday, May 15, 2026, 4:30 pm
This work will also be presented during the scientific session organized by the HS Foundation:
Session details
Date: Thursday, May 14
Time: 7:00 am – 8:15 am
Location: Marquette, 3rd Floor
These studies demonstrate how 3D tissue imaging can support:
visualization of cellular and structural features across intact tissue
spatial analysis of immune and neural components within the disease context
quantitative assessment of tissue organization beyond section-based approaches
Together, these presentations reflect ongoing efforts to apply 3D tissue imaging and spatial profiling to better understand dermatological disease architecture and biology.
