# Alpenglow Biosciences

Alpenglow Biosciences develops 3D tissue imaging and AI technologies that capture, reconstruct, and quantify biology across intact tissue volumes, enabling researchers to study tissue architecture, spatial organization, and disease heterogeneity in three dimensions.

Alpenglow combines 3D tissue imaging, computational analysis, and AI to measure biological structures and spatial relationships throughout intact tissue volumes. This approach preserves tissue architecture and heterogeneity that can be difficult to characterize from conventional thin tissue sections alone.

The Aurora 3D™ platform integrates Open-Top Light-Sheet microscopy (OTLS), tissue processing, data management, and AI-powered quantitative analysis. Alpenglow offers both contract research services for pharmaceutical and biotechnology organizations and 3Di™ OTLS microscopy systems for research institutions and imaging facilities.

Summit AI™ is Alpenglow's AI and multimodal data platform for transforming large-scale tissue imaging data into quantitative biological readouts, including measurements of tissue architecture, cellular organization, spatial relationships, heterogeneity, and disease-associated features.

Applications span dermatology, oncology, immunology, neuroscience, fibrosis, gastrointestinal research, and other areas where understanding tissue biology in three dimensions can provide information beyond conventional section-based analysis.

Alpenglow works with pharmaceutical and biotechnology companies, academic researchers, pathology groups, and imaging facilities to apply quantitative 3D spatial biology to research and drug development.